The c. 1838 Clayton House served as a Union command post during the Battle of Allatoona Pass on October 5, 1864, and then as a field hospital for both sides after the battle. Accounts tell of amputated limbs being tossed from the front balcony into a wagon collecting them for disposal. Bloodstains on the floor and bullet holes in the walls are still visible—a marker on the lawn honors 21 unidentified soldiers buried in the backyard after the battle.

The house, now known as the Clayton-Mooney House, is privately owned and not open to the public except for tours during the annual Civil War encampment at Allatoona in October.